課程資訊
課程名稱
疾病篩檢統計
Statistics in Disease Screening 
開課學期
112-2 
授課對象
公共衛生學院  流行病學與預防醫學研究所  
授課教師
陳秀熙 
課號
EPM7189 
課程識別碼
849 M0840 
班次
 
學分
2.0 
全/半年
半年 
必/選修
選修 
上課時間
星期一8,9(15:30~17:20) 
上課地點
公衛101 
備註
本課程中文授課,使用英文教科書。非同步遠距教學。
總人數上限:45人 
 
課程簡介影片
 
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課程概述

本課程主授疾病篩檢方法論與應用實務,以統計觀點切入,自研究設計著手探討篩檢計畫之評估方式,並討論篩檢敏感度、平均滯留期、篩檢偵測模式與疾病多階段模式於疾病篩檢之應用。 (The contents of the course put emphasis on both methodology and practice of disease screening based on statistical viewpoint. We begin with study design of evaluation of disease screening, and then impart how to build up temporal natural history model to estimate mean sojourn time and sensitivity both of which are responsible for evaluation of disease screening. We also make students understand the application of multi-state model to evaluation of disease screening.) 

課程目標
本課程旨於幫助學生了解疾病篩檢在公共衛生和醫學領域中重要性及其應用。課程中包含各疾病實例如: 癌症及COVID-19等應用,使學生可以透過非同步線上課程反覆學習消化課程內容。
The goal of this course is to help students comprehend the importance and applications of disease screening in public health and medicine. Screening for cancers and infectious diseases like COVID-19 would be covered through this non-synchronize online course that renders students feasible for the repeated excursions of the course to digest the contents. 
課程要求
Basic epidemiology, Basic statistics 
預期每週課後學習時數
 
Office Hours
另約時間 備註: 有任何課程問題或加選問題,請來信詢問助教(楊長融,r11849034@ntu.edu.tw或jeff88.ynag@gmail.com) 
指定閱讀
待補 
參考書目
Chiu HM, Chen HH, editors. Colorectal Cancer Screening: Theory and Practical Application. Springer Nature; 2020 Nov 20

Breslow NE, Day NE. Statistical Methods in Cancer Research Volume II: The Design and Analysis of Cohort Studies. IARC Scientific Publication No. 82; 1986.

Breslow NE, Day NE. Statistical Methods in Cancer Research Volume I-The Analysis of Case-control Studies. IARC Scientific Publication No. 32; 1980. 
評量方式
(僅供參考)
 
No.
項目
百分比
說明
1. 
線上課程參與及評量 
40% 
 
2. 
期中測驗(實體) 
30% 
 
3. 
期末測驗(實體) 
30% 
 
 
課程進度
週次
日期
單元主題
第1週
2/19  Introduction to Disease Screening  
第2週
2/26  Introduction to Theory and Practice of Health Checkup 
第3週
3/04  Indicators for Evaluation of Screening Program 
第4週
3/11  Experimental Design of Disease Screening 
第5週
3/18  Breast Cancer Screening Evolution 
第6週
3/25  Natural History in Disease Progression (I) 
第7週
4/01  Natural History in Disease Progression (II) 
第8週
4/08  Midterm Exam (In person) 
第9週
4/15  Evaluation of population-based screening program (I) 
第10週
4/22  Evaluation of population-based screening program (II) 
第11週
4/29  Meta-analysis of Breast Cancer 
第12週
5/06  Performance indicator of Disease Screening 
第13週
5/13  Evidence-based Medicine in Disease Screening (I) 
第14週
5/20  Evidence-based Medicine in Disease Screening (II) 
第15週
5/27  Screening for Pulmonary Tuberculosis 
第16週
6/3  Final exam (In person)